Endotoxins enhance hepatocarcinogenesis induced by oral intake of thioacetamide in rats*
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چکیده
منابع مشابه
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15 صفحه اولThe effects of Artemisia aucheri extract on hepatotoxicity induced by thioacetamide in male rats
Objective: Liver is an important organ that is exposed to many oxidant and carcinogenic agents, thus antioxidant compounds are beneficial for liver health. Artemisia contains flavonoid compounds and anti-diabetic, antioxidant, and anti-inflammatory properties. Due to possessing terpene and sesquiterpene compounds, this plant has antioxidant properties. This study was done to investigate the eff...
متن کاملEffect of oral administration of ethanolic extract of Vitex negundo on thioacetamide-induced nephrotoxicity in rats
BACKGROUND Oxidative stress due to abnormal induction of reactive oxygen species (ROS) molecules is believed to be involved in the etiology of many diseases. Evidences suggest that ROS is involved in nephrotoxicity through frequent exposure to industrial toxic agents such as thioacetamide (TAA). The current investigation was designed to explore the possible protective effects of the leaves of V...
متن کاملDietary nucleotides correct plasma and liver microsomal fatty acid alterations in rats with liver cirrhosis induced by oral intake of thioacetamide.
BACKGROUND/AIMS Dietary nucleotides modulate a number of metabolic processes, including long-chain polyunsaturated fatty acid metabolism. In this study, we evaluated the effect of dietary nucleotides on plasma and liver microsomal fatty acid profiles in a rat model of liver cirrhosis induced by oral intake of thioacetamide. METHODS Fifty-four female Wistar rats were assigned to one of the fol...
متن کاملRegenerative Effect of Bone Marrow-derived Mesenchymal Stem Cells in Thioacetamide-induced Liver Fibrosis of Rats
The present study determined the regenerative effect of bone marrow-derived stem cells (BMSCs) on thioacetamide (TA)-induced liver fibrosis in rats. A total of 30 male Wistar rats were randomly divided into sham control and treatment groups. The rats of the sham control group were subdivided into three groups and sampled on the 14th, 18th, and 20th weeks after fibrosis induction. The rats of th...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 1998
ISSN: 1007-9327
DOI: 10.3748/wjg.v4.i2.128